Endoscopic studies of nabumetone in patients with rheumatoid arthritis: A comparative endoscopic and histologic evaluation

Gastric tolerance to 1 g of nabumetone administered in a single nightly dose was assessed in two trials in patients with rheumatoid arthritis. Gastroscopy and histology of mucosal biopsy specimens were performed before and after the end of treatment in both trials. Trial 1 was an open study that com...

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Veröffentlicht in:	The American journal of medicine 1987-10, Vol.83 (4), p.19-24
Hauptverfasser:	Greb, Wolfgang H., von Schrader, Hans W., Čerlek, Svebor, Dominis, Mara, Hauptmann, Eric, Zenić, Nada
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis, Rheumatoid - drug therapy Biopsy Butanones - administration & dosage Butanones - adverse effects Butanones - therapeutic use Clinical Trials as Topic Drug Administration Schedule Female Gastric Mucosa - drug effects Gastric Mucosa - pathology Gastroscopy Humans Indomethacin - administration & dosage Indomethacin - adverse effects Indomethacin - therapeutic use Male Middle Aged Nabumetone Naproxen - administration & dosage Naproxen - adverse effects Naproxen - therapeutic use Random Allocation
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