CD4 and CD8 Lymphocyte Counts as Surrogate Early Markers for Progression in SARS-CoV-2 Pneumonia: A Prospective Study

Background: COVID-19 pathophysiology and the predictive factors involved are not fully understood, but lymphocytes dysregulation appears to play a role. This paper aims to evaluate lymphocyte subsets in the pathophysiology of COVID-19 and as predictive factors for severe disease. Patient and methods...

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Veröffentlicht in:	Viruses 2020-11, Vol.12 (11), p.1277, Article 1277
Hauptverfasser:	Calvet, Joan, Gratacos, Jordi, Amengual, Maria Jose, Llop, Maria, Navarro, Marta, Moreno, Amalia, Berenguer-Llergo, Antoni, Serrano, Alejandra, Orellana, Cristobal, Cervantes, Manel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Area Under Curve Biomarkers - analysis CD4+ T cells CD4-CD8 Ratio - statistics & numerical data CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - pathology CD4-Positive T-Lymphocytes - virology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - pathology CD8-Positive T-Lymphocytes - virology COVID-19 COVID-19 - diagnosis COVID-19 - immunology COVID-19 - pathology COVID-19 - virology Disease Progression Female Humans Life Sciences & Biomedicine Lung Lymphocyte Count lymphocyte subsets Lymphocyte Subsets - immunology Lymphocyte Subsets - pathology Lymphocyte Subsets - virology Male Middle Aged Patient Discharge - statistics & numerical data predictive value Prognosis Prospective Studies ROC Curve SARS-CoV-2 - immunology SARS-CoV-2 - pathogenicity Science & Technology severity Severity of Illness Index Virology
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