Disruption of estradiol regulation of orexin neurons: a novel mechanism in excessive ventilatory response to CO 2 inhalation in a female rat model of panic disorder

Panic disorder (PD) is ~2 times more frequent in women. An excessive ventilatory response to CO inhalation is more likely during the premenstrual phase. While ovarian hormones appear important in the pathophysiology of PD, their role remains poorly understood as female animals are rarely used in pre...

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Veröffentlicht in:	Translational psychiatry 2020-11, Vol.10 (1), p.394
Hauptverfasser:	Tenorio-Lopes, Luana, Fournier, Stéphanie, Henry, Mathilde S, Bretzner, Frédéric, Kinkead, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Carbon Dioxide Estradiol - pharmacology Female Maternal Deprivation Neurons Orexins Panic Disorder Pulmonary Ventilation Rats Rats, Sprague-Dawley Sexual Maturation
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