Hydroxyapatite–Bovine Serum Albumin–Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma

Osteosarcoma is the most primary type of bone tumor occurring in the pediatric and adolescent age groups. In order to obtain the most appropriate prognosis, both tumor recurrence inhibition and bone repair promotion are required. In this study, a ternary nanoscale biomaterial/antitumor drug complex...

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Veröffentlicht in:	Advanced healthcare materials 2021-01, Vol.10 (2), p.e2000573-n/a, Article 2000573
Hauptverfasser:	Liu, Yongjia, Qiao, Zhiguang, Gao, Jian, Wu, Fengren, Sun, Binbin, Lian, Meifei, Qian, Jiwen, Su, Yue, Zhu, Xinyuan, Zhu, Bangshang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Alkaline phosphatase Anticancer properties Antitumor activity anti‐tumors Biocompatibility Biomedical materials Bone biomaterials Bone cancer Bone healing Bone tumors Bovine serum albumin bovine serum albumins Calcium Calcium ions Cell Line, Tumor Cell migration Cell proliferation Child Controlled release Cytotoxicity Differentiation (biology) Drug Carriers Drug delivery systems Durapatite Engineering Engineering, Biomedical Fetuses Humans Hydroxyapatite hydroxyapatites Materials Science Materials Science, Biomaterials Mechanical loading Metastases Nanoparticles Nanoscience & Nanotechnology Osteoblasts Osteogenesis Osteosarcoma Osteosarcoma - drug therapy osteosarcomas Paclitaxel Paclitaxel - pharmacology Pediatrics Polymerase chain reaction Reverse transcription Sarcoma Science & Technology Science & Technology - Other Topics Serum albumin Serum Albumin, Bovine Sustained release Technology Toxicity
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