Water Loss in Aging Erythrocytes Provides a Clue to a General Mechanism of Cellular Senescence
Experimental evidence for age-dependent loss of intracellular water content as a widespread concomitant of cellular senescence is reviewed. Quantitative models are presented, indicating that an age-dependent increase in macromolecular crowding resulting from water loss may be responsible for three o...
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Veröffentlicht in: | Biophysical journal 2020-11, Vol.119 (10), p.2039-2044 |
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Sprache: | eng |
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