Water Loss in Aging Erythrocytes Provides a Clue to a General Mechanism of Cellular Senescence

Experimental evidence for age-dependent loss of intracellular water content as a widespread concomitant of cellular senescence is reviewed. Quantitative models are presented, indicating that an age-dependent increase in macromolecular crowding resulting from water loss may be responsible for three o...

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Veröffentlicht in:Biophysical journal 2020-11, Vol.119 (10), p.2039-2044
1. Verfasser: Minton, Allen P.
Format: Artikel
Sprache:eng
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