Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study
Objective The usefulness of the modified Glasgow prognostic score (GPS) as a prognostic tool remains unclear for patients undergoing curative surgery for intrahepatic cholangiocarcinoma (ICC). Therefore, this study investigated the prognostic usefulness of the GPS for patients who underwent ICC surg...
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| Veröffentlicht in: | World journal of surgery 2021-01, Vol.45 (1), p.279-290 |
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| creator | Sui, Kenta Okabayashi, Takehiro Umeda, Yuzo Oishi, Masahiro Kojima, Toru Sato, Daisuke Endo, Yoshikatsu Ota, Tetsuya Hioki, Katsuyoshi Inagaki, Masaru Matsuda, Tadakazu Hirai, Ryuji Kimura, Masashi Yagi, Takahito Fujiwara, Toshiyoshi |
| description | Objective
The usefulness of the modified Glasgow prognostic score (GPS) as a prognostic tool remains unclear for patients undergoing curative surgery for intrahepatic cholangiocarcinoma (ICC). Therefore, this study investigated the prognostic usefulness of the GPS for patients who underwent ICC surgery.
Method
All ICC patients who had a curative-intent hepatectomy at 17 institutions between 2000 and 2016 were included. The correlation was assessed between the preoperative GPS and the baseline characteristics of the patients, histopathological parameters, surgical parameters, and the postresection overall survival (OS).
Result
There were 273 patients who met the eligibility criteria between the years 2000 and 2016. The postoperative OS rates at 1, 3, and 5 years were 83.8%, 56.3%, and 41.5%, respectively (median OS, 47.7 months). A multivariate analysis revealed the factors that were associated with a worse OS, which included an increased GPS (hazard ratio = 1.62; 95% confidence interval [CI]: 1.01–2.53;
P
= 0.03), an elevated carcinoembryonic antigen level (hazard ratio = 1.60; 95% CI: 1.06–2.41;
P
= 0.02), an elevated carbohydrate antigen 19–9 level (hazard ratio = 1.55; 95% CI: 1.05–2.30;
P
= 0.03), undifferentiated carcinoma (hazard ratio = 2.41; 95% CI: 1.56–3.67;
P
|
| doi_str_mv | 10.1007/s00268-020-05797-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_32989578</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2473220448</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5362-d21c17bb4fbbffdfb3071a1ff62d73c5f7eb735695c2839b6af7b6b6a736e5413</originalsourceid><addsrcrecordid>eNqNkU9v0zAYhyMEYt3gC3BAlrggTYHXf2Knu5WKjaGiIbqJY-Q4duspiTvbYer34YPiNmUgDmgX24fn-fm1f1n2CsM7DCDeBwDCyxwI5FCIqcjZk2yCGSU5oYQ-zSZAOUtnTI-y4xBuAbDgwJ9nR5RMy2khykn286t3q96FaBW6iba1cYucQXGt0UUrw8rdo7-IpXJeI-P8Hli4fpVfa9-hqyEq1-mAZiZqjxb2R1q_6aBVtK7fC5d99HKtN3KXM1-7VvYr65T0yvauk2dohr4MbbS57dNVcdiJskXLODTbF9kzI9ugXx72k-zm_OP1_FO-uLq4nM8WuSooJ3lDsMKirpmpa2MaU1MQWGJjOGkEVYURuha04NNCkZJOay6NqHnaBOW6YJieZG_H3I13d4MOsepsULpNs2o3hIowJiiUFPOEvvkHvXWDTxPvKEEJAcbKRJGRUt6F4LWpNt520m8rDNWuw2rssEodVvsOK5ak14fooe5086D8Li0B5Qjc69qZoKzulX7AAFIQZYSkfAA6t1Hu_nLuhj4m9fTxaqLPDrRt9fYRs1ffPy8_nAOUmCSZjnJIXr_S_s8P_efxvwB-y9vW</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2473220448</pqid></control><display><type>article</type><title>Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study</title><source>SpringerNature Journals</source><source>Access via Wiley Online Library</source><source>Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><creator>Sui, Kenta ; Okabayashi, Takehiro ; Umeda, Yuzo ; Oishi, Masahiro ; Kojima, Toru ; Sato, Daisuke ; Endo, Yoshikatsu ; Ota, Tetsuya ; Hioki, Katsuyoshi ; Inagaki, Masaru ; Matsuda, Tadakazu ; Hirai, Ryuji ; Kimura, Masashi ; Yagi, Takahito ; Fujiwara, Toshiyoshi</creator><creatorcontrib>Sui, Kenta ; Okabayashi, Takehiro ; Umeda, Yuzo ; Oishi, Masahiro ; Kojima, Toru ; Sato, Daisuke ; Endo, Yoshikatsu ; Ota, Tetsuya ; Hioki, Katsuyoshi ; Inagaki, Masaru ; Matsuda, Tadakazu ; Hirai, Ryuji ; Kimura, Masashi ; Yagi, Takahito ; Fujiwara, Toshiyoshi</creatorcontrib><description>Objective
The usefulness of the modified Glasgow prognostic score (GPS) as a prognostic tool remains unclear for patients undergoing curative surgery for intrahepatic cholangiocarcinoma (ICC). Therefore, this study investigated the prognostic usefulness of the GPS for patients who underwent ICC surgery.
Method
All ICC patients who had a curative-intent hepatectomy at 17 institutions between 2000 and 2016 were included. The correlation was assessed between the preoperative GPS and the baseline characteristics of the patients, histopathological parameters, surgical parameters, and the postresection overall survival (OS).
Result
There were 273 patients who met the eligibility criteria between the years 2000 and 2016. The postoperative OS rates at 1, 3, and 5 years were 83.8%, 56.3%, and 41.5%, respectively (median OS, 47.7 months). A multivariate analysis revealed the factors that were associated with a worse OS, which included an increased GPS (hazard ratio = 1.62; 95% confidence interval [CI]: 1.01–2.53;
P
= 0.03), an elevated carcinoembryonic antigen level (hazard ratio = 1.60; 95% CI: 1.06–2.41;
P
= 0.02), an elevated carbohydrate antigen 19–9 level (hazard ratio = 1.55; 95% CI: 1.05–2.30;
P
= 0.03), undifferentiated carcinoma (hazard ratio = 2.41; 95% CI: 1.56–3.67;
P
< 0.01), and positive metastasis to the lymph nodes (hazard ratio = 2.54; 95% CI: 1.76–3.67;
P
< 0.01). In ICC patients after a hepatectomy, an elevated GPS was associated with poorer OS, even if the tumour factors that affected GPS were eliminated by propensity-score matching.
Conclusion
Preoperative GPS can be useful to predict the postoperative outcomes of ICC patients. Therefore, this relatively simple and inexpensive scoring system can be utilized to further refine patient stratification as well as to predict survival.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-020-05797-4</identifier><identifier>PMID: 32989578</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Antigens ; Carbohydrates ; Carcinoembryonic antigen ; Cardiac Surgery ; Cholangiocarcinoma ; Confidence intervals ; General Surgery ; Health hazards ; Hepatectomy ; Life Sciences & Biomedicine ; Lymph nodes ; Medicine ; Medicine & Public Health ; Metastases ; Multivariate analysis ; Original Scientific Report ; Parameters ; Science & Technology ; Surgery ; Survival ; Thoracic Surgery ; Tumors ; Vascular Surgery</subject><ispartof>World journal of surgery, 2021-01, Vol.45 (1), p.279-290</ispartof><rights>Société Internationale de Chirurgie 2020</rights><rights>2021 The Author(s) under exclusive licence to Société Internationale de Chirurgie</rights><rights>Société Internationale de Chirurgie 2020.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>4</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000573422100003</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c5362-d21c17bb4fbbffdfb3071a1ff62d73c5f7eb735695c2839b6af7b6b6a736e5413</citedby><cites>FETCH-LOGICAL-c5362-d21c17bb4fbbffdfb3071a1ff62d73c5f7eb735695c2839b6af7b6b6a736e5413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00268-020-05797-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00268-020-05797-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,39263,41493,42562,45579,45580,51324</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32989578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sui, Kenta</creatorcontrib><creatorcontrib>Okabayashi, Takehiro</creatorcontrib><creatorcontrib>Umeda, Yuzo</creatorcontrib><creatorcontrib>Oishi, Masahiro</creatorcontrib><creatorcontrib>Kojima, Toru</creatorcontrib><creatorcontrib>Sato, Daisuke</creatorcontrib><creatorcontrib>Endo, Yoshikatsu</creatorcontrib><creatorcontrib>Ota, Tetsuya</creatorcontrib><creatorcontrib>Hioki, Katsuyoshi</creatorcontrib><creatorcontrib>Inagaki, Masaru</creatorcontrib><creatorcontrib>Matsuda, Tadakazu</creatorcontrib><creatorcontrib>Hirai, Ryuji</creatorcontrib><creatorcontrib>Kimura, Masashi</creatorcontrib><creatorcontrib>Yagi, Takahito</creatorcontrib><creatorcontrib>Fujiwara, Toshiyoshi</creatorcontrib><title>Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>WORLD J SURG</addtitle><addtitle>World J Surg</addtitle><description>Objective
The usefulness of the modified Glasgow prognostic score (GPS) as a prognostic tool remains unclear for patients undergoing curative surgery for intrahepatic cholangiocarcinoma (ICC). Therefore, this study investigated the prognostic usefulness of the GPS for patients who underwent ICC surgery.
Method
All ICC patients who had a curative-intent hepatectomy at 17 institutions between 2000 and 2016 were included. The correlation was assessed between the preoperative GPS and the baseline characteristics of the patients, histopathological parameters, surgical parameters, and the postresection overall survival (OS).
Result
There were 273 patients who met the eligibility criteria between the years 2000 and 2016. The postoperative OS rates at 1, 3, and 5 years were 83.8%, 56.3%, and 41.5%, respectively (median OS, 47.7 months). A multivariate analysis revealed the factors that were associated with a worse OS, which included an increased GPS (hazard ratio = 1.62; 95% confidence interval [CI]: 1.01–2.53;
P
= 0.03), an elevated carcinoembryonic antigen level (hazard ratio = 1.60; 95% CI: 1.06–2.41;
P
= 0.02), an elevated carbohydrate antigen 19–9 level (hazard ratio = 1.55; 95% CI: 1.05–2.30;
P
= 0.03), undifferentiated carcinoma (hazard ratio = 2.41; 95% CI: 1.56–3.67;
P
< 0.01), and positive metastasis to the lymph nodes (hazard ratio = 2.54; 95% CI: 1.76–3.67;
P
< 0.01). In ICC patients after a hepatectomy, an elevated GPS was associated with poorer OS, even if the tumour factors that affected GPS were eliminated by propensity-score matching.
Conclusion
Preoperative GPS can be useful to predict the postoperative outcomes of ICC patients. Therefore, this relatively simple and inexpensive scoring system can be utilized to further refine patient stratification as well as to predict survival.</description><subject>Abdominal Surgery</subject><subject>Antigens</subject><subject>Carbohydrates</subject><subject>Carcinoembryonic antigen</subject><subject>Cardiac Surgery</subject><subject>Cholangiocarcinoma</subject><subject>Confidence intervals</subject><subject>General Surgery</subject><subject>Health hazards</subject><subject>Hepatectomy</subject><subject>Life Sciences & Biomedicine</subject><subject>Lymph nodes</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastases</subject><subject>Multivariate analysis</subject><subject>Original Scientific Report</subject><subject>Parameters</subject><subject>Science & Technology</subject><subject>Surgery</subject><subject>Survival</subject><subject>Thoracic Surgery</subject><subject>Tumors</subject><subject>Vascular Surgery</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkU9v0zAYhyMEYt3gC3BAlrggTYHXf2Knu5WKjaGiIbqJY-Q4duspiTvbYer34YPiNmUgDmgX24fn-fm1f1n2CsM7DCDeBwDCyxwI5FCIqcjZk2yCGSU5oYQ-zSZAOUtnTI-y4xBuAbDgwJ9nR5RMy2khykn286t3q96FaBW6iba1cYucQXGt0UUrw8rdo7-IpXJeI-P8Hli4fpVfa9-hqyEq1-mAZiZqjxb2R1q_6aBVtK7fC5d99HKtN3KXM1-7VvYr65T0yvauk2dohr4MbbS57dNVcdiJskXLODTbF9kzI9ugXx72k-zm_OP1_FO-uLq4nM8WuSooJ3lDsMKirpmpa2MaU1MQWGJjOGkEVYURuha04NNCkZJOay6NqHnaBOW6YJieZG_H3I13d4MOsepsULpNs2o3hIowJiiUFPOEvvkHvXWDTxPvKEEJAcbKRJGRUt6F4LWpNt520m8rDNWuw2rssEodVvsOK5ak14fooe5086D8Li0B5Qjc69qZoKzulX7AAFIQZYSkfAA6t1Hu_nLuhj4m9fTxaqLPDrRt9fYRs1ffPy8_nAOUmCSZjnJIXr_S_s8P_efxvwB-y9vW</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Sui, Kenta</creator><creator>Okabayashi, Takehiro</creator><creator>Umeda, Yuzo</creator><creator>Oishi, Masahiro</creator><creator>Kojima, Toru</creator><creator>Sato, Daisuke</creator><creator>Endo, Yoshikatsu</creator><creator>Ota, Tetsuya</creator><creator>Hioki, Katsuyoshi</creator><creator>Inagaki, Masaru</creator><creator>Matsuda, Tadakazu</creator><creator>Hirai, Ryuji</creator><creator>Kimura, Masashi</creator><creator>Yagi, Takahito</creator><creator>Fujiwara, Toshiyoshi</creator><general>Springer International Publishing</general><general>Springer Nature</general><general>Springer Nature B.V</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>202101</creationdate><title>Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study</title><author>Sui, Kenta ; Okabayashi, Takehiro ; Umeda, Yuzo ; Oishi, Masahiro ; Kojima, Toru ; Sato, Daisuke ; Endo, Yoshikatsu ; Ota, Tetsuya ; Hioki, Katsuyoshi ; Inagaki, Masaru ; Matsuda, Tadakazu ; Hirai, Ryuji ; Kimura, Masashi ; Yagi, Takahito ; Fujiwara, Toshiyoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5362-d21c17bb4fbbffdfb3071a1ff62d73c5f7eb735695c2839b6af7b6b6a736e5413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Abdominal Surgery</topic><topic>Antigens</topic><topic>Carbohydrates</topic><topic>Carcinoembryonic antigen</topic><topic>Cardiac Surgery</topic><topic>Cholangiocarcinoma</topic><topic>Confidence intervals</topic><topic>General Surgery</topic><topic>Health hazards</topic><topic>Hepatectomy</topic><topic>Life Sciences & Biomedicine</topic><topic>Lymph nodes</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastases</topic><topic>Multivariate analysis</topic><topic>Original Scientific Report</topic><topic>Parameters</topic><topic>Science & Technology</topic><topic>Surgery</topic><topic>Survival</topic><topic>Thoracic Surgery</topic><topic>Tumors</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sui, Kenta</creatorcontrib><creatorcontrib>Okabayashi, Takehiro</creatorcontrib><creatorcontrib>Umeda, Yuzo</creatorcontrib><creatorcontrib>Oishi, Masahiro</creatorcontrib><creatorcontrib>Kojima, Toru</creatorcontrib><creatorcontrib>Sato, Daisuke</creatorcontrib><creatorcontrib>Endo, Yoshikatsu</creatorcontrib><creatorcontrib>Ota, Tetsuya</creatorcontrib><creatorcontrib>Hioki, Katsuyoshi</creatorcontrib><creatorcontrib>Inagaki, Masaru</creatorcontrib><creatorcontrib>Matsuda, Tadakazu</creatorcontrib><creatorcontrib>Hirai, Ryuji</creatorcontrib><creatorcontrib>Kimura, Masashi</creatorcontrib><creatorcontrib>Yagi, Takahito</creatorcontrib><creatorcontrib>Fujiwara, Toshiyoshi</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Proquest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sui, Kenta</au><au>Okabayashi, Takehiro</au><au>Umeda, Yuzo</au><au>Oishi, Masahiro</au><au>Kojima, Toru</au><au>Sato, Daisuke</au><au>Endo, Yoshikatsu</au><au>Ota, Tetsuya</au><au>Hioki, Katsuyoshi</au><au>Inagaki, Masaru</au><au>Matsuda, Tadakazu</au><au>Hirai, Ryuji</au><au>Kimura, Masashi</au><au>Yagi, Takahito</au><au>Fujiwara, Toshiyoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><stitle>WORLD J SURG</stitle><addtitle>World J Surg</addtitle><date>2021-01</date><risdate>2021</risdate><volume>45</volume><issue>1</issue><spage>279</spage><epage>290</epage><pages>279-290</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Objective
The usefulness of the modified Glasgow prognostic score (GPS) as a prognostic tool remains unclear for patients undergoing curative surgery for intrahepatic cholangiocarcinoma (ICC). Therefore, this study investigated the prognostic usefulness of the GPS for patients who underwent ICC surgery.
Method
All ICC patients who had a curative-intent hepatectomy at 17 institutions between 2000 and 2016 were included. The correlation was assessed between the preoperative GPS and the baseline characteristics of the patients, histopathological parameters, surgical parameters, and the postresection overall survival (OS).
Result
There were 273 patients who met the eligibility criteria between the years 2000 and 2016. The postoperative OS rates at 1, 3, and 5 years were 83.8%, 56.3%, and 41.5%, respectively (median OS, 47.7 months). A multivariate analysis revealed the factors that were associated with a worse OS, which included an increased GPS (hazard ratio = 1.62; 95% confidence interval [CI]: 1.01–2.53;
P
= 0.03), an elevated carcinoembryonic antigen level (hazard ratio = 1.60; 95% CI: 1.06–2.41;
P
= 0.02), an elevated carbohydrate antigen 19–9 level (hazard ratio = 1.55; 95% CI: 1.05–2.30;
P
= 0.03), undifferentiated carcinoma (hazard ratio = 2.41; 95% CI: 1.56–3.67;
P
< 0.01), and positive metastasis to the lymph nodes (hazard ratio = 2.54; 95% CI: 1.76–3.67;
P
< 0.01). In ICC patients after a hepatectomy, an elevated GPS was associated with poorer OS, even if the tumour factors that affected GPS were eliminated by propensity-score matching.
Conclusion
Preoperative GPS can be useful to predict the postoperative outcomes of ICC patients. Therefore, this relatively simple and inexpensive scoring system can be utilized to further refine patient stratification as well as to predict survival.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>32989578</pmid><doi>10.1007/s00268-020-05797-4</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | World journal of surgery, 2021-01, Vol.45 (1), p.279-290 |
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| language | eng |
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| source | SpringerNature Journals; Access via Wiley Online Library; Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /> |
| subjects | Abdominal Surgery Antigens Carbohydrates Carcinoembryonic antigen Cardiac Surgery Cholangiocarcinoma Confidence intervals General Surgery Health hazards Hepatectomy Life Sciences & Biomedicine Lymph nodes Medicine Medicine & Public Health Metastases Multivariate analysis Original Scientific Report Parameters Science & Technology Surgery Survival Thoracic Surgery Tumors Vascular Surgery |
| title | Prognostic Utility of the Glasgow Prognostic Score for the Long-Term Outcomes After Liver Resection for Intrahepatic Cholangiocarcinoma: A Multi-institutional Study |
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