Advantages and Pitfalls of Capillary Electrophoresis of Pharmaceutical Compounds and Their Enantiomers in Complex Samples: Comparison of Hydrodynamically Opened and Closed Systems

Several research disciplines require fast, reliable and highly automated determination of pharmaceutically active compounds and their enantiomers in complex biological matrices. To address some of the challenges of Capillary Electrophoresis (CE), such as low concentration sensitivity and performance...

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Veröffentlicht in:	International journal of molecular sciences 2020-09, Vol.21 (18), p.6852, Article 6852
Hauptverfasser:	Masar, Marian, Hradski, Jasna, Schmid, Martin G., Szucs, Roman
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry & Molecular Biology Capillary electrophoresis Chemistry Chemistry, Multidisciplinary chiral separation Electrophoresis, Capillary - instrumentation Electrophoresis, Capillary - methods hydrodynamically opened and closed systems Hydrodynamics Life Sciences & Biomedicine pharmaceutical analysis Pharmaceutical Preparations Physical Sciences Pindolol - analysis Propranolol - analysis Reproducibility of Results Science & Technology Sensitivity and Specificity Serum - chemistry serum analysis Software Stereoisomerism
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