CYP2S1 might regulate proliferation and immune response of keratinocyte in psoriasis

Psoriasis is an autoimmune skin disorder influenced by genetic, epigenetic and environmental factors. We previously found CYP2S1 intragenic DNA methylation cg19430423 site strongly hypomethylated in psoriatic skin tissues. In this study, we performed methylation loci fine-mapping to search the top s...

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Veröffentlicht in:	Epigenetics 2021-06, Vol.16 (6), p.618-628
Hauptverfasser:	Sheng, Yujun, Wen, Leilei, Zheng, Xiaodong, Li, Mengqing, Wang, Dan, Chen, Sixian, Li, Ran, Tang, Lili, Zhou, Fusheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation CYP2S1 gene Cytochrome P-450 Enzyme System - genetics DNA Methylation Humans keratinocyte Keratinocytes - immunology Psoriasis Psoriasis - genetics Psoriasis - immunology Research Paper
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