Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity

cGAS/STING signaling plays an essential role in sensing cytosolic DNA. cGAS activity is regulated by posttranslational modifications and binding partners. cGAS interactome largely includes mammalian or viral proteins. Whether and how bacterial proteins bind cGAS to modulate innate immunity remain el...

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Veröffentlicht in:	iScience 2020-09, Vol.23 (9), p.101463, Article 101463
Hauptverfasser:	Zhang, Yanqiong, Ma, Zhe, Wang, Ying, Boyer, Joshua, Ni, Guoxin, Cheng, Liang, Su, Siyuan, Zhang, Zhigang, Zhu, Zhichuan, Qian, Jiayi, Su, Lishan, Zhang, Qi, Damania, Blossom, Liu, Pengda
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Immunology Microbiology Multidisciplinary Sciences Science & Technology Science & Technology - Other Topics
Online-Zugang:	Volltext
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