Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review
In this era, there is a global concern in the use of bioactive molecules such as chitosan in the field of antimicrobial and antioxidant benefits. Because of its biodegradability, biological compatibility, antimicrobial, antioxidants activity, and high safety, chitosan could be used in a large number...
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| Veröffentlicht in: | International journal of biological macromolecules 2020-12, Vol.164, p.2726-2744 |
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| creator | Abd El-Hack, Mohamed E. El-Saadony, Mohamed T. Shafi, Manal E. Zabermawi, Nidal M. Arif, Muhammad Batiha, Gaber Elsaber Khafaga, Asmaa F. Abd El-Hakim, Yasmina M. Al-Sagheer, Adham A. |
| description | In this era, there is a global concern in the use of bioactive molecules such as chitosan in the field of antimicrobial and antioxidant benefits. Because of its biodegradability, biological compatibility, antimicrobial, antioxidants activity, and high safety, chitosan could be used in a large number of applications. It could exist in many forms, such as fibers, gels, films, sponges, nanoparticles, and beads. The different biological activities of chitosan and its products are extensively investigated to broaden the application fields in several areas. Chitosan's natural properties depend strongly on water and other solvent solubility. Consequently, the chitosan oligosaccharides with a low polymerization degree are getting significant attention in the pharmaceutical and medical applications because they have lower viscosity and higher water solubility than chitosan. The objective of this review article is to put the antioxidant and antimicrobial properties of chitosan and its derivatives under the spotlight. The impacts of chitosan on physicochemical parameters like molecular weight and deacetylation degree on its bioactivities are also identified. Additionally, other applications of chitosan and its derivatives, including wound healing products, wastewater treatment, and cosmetics, have also been highlighted. |
| doi_str_mv | 10.1016/j.ijbiomac.2020.08.153 |
| format | Article |
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Because of its biodegradability, biological compatibility, antimicrobial, antioxidants activity, and high safety, chitosan could be used in a large number of applications. It could exist in many forms, such as fibers, gels, films, sponges, nanoparticles, and beads. The different biological activities of chitosan and its products are extensively investigated to broaden the application fields in several areas. Chitosan's natural properties depend strongly on water and other solvent solubility. Consequently, the chitosan oligosaccharides with a low polymerization degree are getting significant attention in the pharmaceutical and medical applications because they have lower viscosity and higher water solubility than chitosan. The objective of this review article is to put the antioxidant and antimicrobial properties of chitosan and its derivatives under the spotlight. The impacts of chitosan on physicochemical parameters like molecular weight and deacetylation degree on its bioactivities are also identified. Additionally, other applications of chitosan and its derivatives, including wound healing products, wastewater treatment, and cosmetics, have also been highlighted.</description><identifier>ISSN: 0141-8130</identifier><identifier>EISSN: 1879-0003</identifier><identifier>DOI: 10.1016/j.ijbiomac.2020.08.153</identifier><identifier>PMID: 32841671</identifier><language>eng</language><publisher>AMSTERDAM: Elsevier B.V</publisher><subject>Acetylation ; Animals ; Anti-Infective Agents - chemistry ; Anti-Infective Agents - pharmacology ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Application ; Biochemistry & Molecular Biology ; Carbohydrate Sequence ; Chemistry ; Chemistry, Applied ; Chitosan - chemistry ; Chitosan - pharmacology ; Chitosan derivatives ; Functional properties ; Humans ; Life Sciences & Biomedicine ; Molecular Weight ; Nanoparticles ; Physical Sciences ; Polymer Science ; Science & Technology ; Waste Water - microbiology ; Water Purification ; Wound Healing - drug effects</subject><ispartof>International journal of biological macromolecules, 2020-12, Vol.164, p.2726-2744</ispartof><rights>2020 Elsevier B.V.</rights><rights>Copyright © 2020 Elsevier B.V. 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Because of its biodegradability, biological compatibility, antimicrobial, antioxidants activity, and high safety, chitosan could be used in a large number of applications. It could exist in many forms, such as fibers, gels, films, sponges, nanoparticles, and beads. The different biological activities of chitosan and its products are extensively investigated to broaden the application fields in several areas. Chitosan's natural properties depend strongly on water and other solvent solubility. Consequently, the chitosan oligosaccharides with a low polymerization degree are getting significant attention in the pharmaceutical and medical applications because they have lower viscosity and higher water solubility than chitosan. The objective of this review article is to put the antioxidant and antimicrobial properties of chitosan and its derivatives under the spotlight. The impacts of chitosan on physicochemical parameters like molecular weight and deacetylation degree on its bioactivities are also identified. Additionally, other applications of chitosan and its derivatives, including wound healing products, wastewater treatment, and cosmetics, have also been highlighted.</description><subject>Acetylation</subject><subject>Animals</subject><subject>Anti-Infective Agents - chemistry</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Application</subject><subject>Biochemistry & Molecular Biology</subject><subject>Carbohydrate Sequence</subject><subject>Chemistry</subject><subject>Chemistry, Applied</subject><subject>Chitosan - chemistry</subject><subject>Chitosan - pharmacology</subject><subject>Chitosan derivatives</subject><subject>Functional properties</subject><subject>Humans</subject><subject>Life Sciences & Biomedicine</subject><subject>Molecular Weight</subject><subject>Nanoparticles</subject><subject>Physical Sciences</subject><subject>Polymer Science</subject><subject>Science & Technology</subject><subject>Waste Water - microbiology</subject><subject>Water Purification</subject><subject>Wound Healing - drug effects</subject><issn>0141-8130</issn><issn>1879-0003</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><sourceid>EIF</sourceid><recordid>eNqNkEFr2zAUgMXoaNOufyH4Puw-WZas7LQQtrVQ6GU7C1l-Ji8klpHUZP33U5o21_UgBE_fJ3gfY3MOFQeu7jYVbTryO-uqGmqoQFdcik9sxnW7KAFAXLAZ8IaXmgu4YtcxbvJUSa4v2ZWodcNVy2eMlmOiHbngO7Lbwo59Pon8X-rzXUzBTxgSYSz8ULg1JR_t-IpRikWPgfY20T6_H2dpjRQKO01bcnnsx_itWBYB94SHL-zzYLcRb9_uG_bn54_fq_vy8enXw2r5WDqhdCqdUguwKGwNVrRaauhhGFQnXY-148MgoVWNbCQ0jciwXOhGZcc1UkrXobhh6vRv3inGgIOZAu1seDEczLGd2Zj3dubYzoA2uV0W5ydxeu522J-191gZ-HoCDtj5ITrC0eEZy3Wl1rAQLUAtZab1x-kVpddeK_88pqx-P6mYO-V2wbzpPQV0yfSe_rfMPx2qpY0</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Abd El-Hack, Mohamed E.</creator><creator>El-Saadony, Mohamed T.</creator><creator>Shafi, Manal E.</creator><creator>Zabermawi, Nidal M.</creator><creator>Arif, Muhammad</creator><creator>Batiha, Gaber Elsaber</creator><creator>Khafaga, Asmaa F.</creator><creator>Abd El-Hakim, Yasmina M.</creator><creator>Al-Sagheer, Adham A.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0003-1216-7003</orcidid><orcidid>https://orcid.org/0000-0001-8633-1836</orcidid><orcidid>https://orcid.org/0000-0003-4235-669X</orcidid><orcidid>https://orcid.org/0000-0002-9895-4106</orcidid><orcidid>https://orcid.org/0000-0003-2899-9496</orcidid></search><sort><creationdate>20201201</creationdate><title>Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review</title><author>Abd El-Hack, Mohamed E. ; 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| subjects | Acetylation Animals Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antioxidants - chemistry Antioxidants - pharmacology Application Biochemistry & Molecular Biology Carbohydrate Sequence Chemistry Chemistry, Applied Chitosan - chemistry Chitosan - pharmacology Chitosan derivatives Functional properties Humans Life Sciences & Biomedicine Molecular Weight Nanoparticles Physical Sciences Polymer Science Science & Technology Waste Water - microbiology Water Purification Wound Healing - drug effects |
| title | Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review |
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