Sex and age differences among tramadol users in three Nordic countries
Introduction: The aim of this study was to examine the prevalence and characteristics of tramadol users in Denmark, Norway and Sweden. Methods: Data from the national prescription databases comprising the entire population of Denmark, Norway and Sweden between 2007 and 2015 were used to assess presc...
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| Veröffentlicht in: | Danish medical journal 2020-07, Vol.67 (7), Article 06190336 |
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| creator | Schelde, Astrid Blicher Sorensen, Anne Mette Skov Hindso, Morten Christensen, Mikkel Bring Jimenez-Solem, Espen Eriksson, Robert |
| description | Introduction: The aim of this study was to examine the prevalence and characteristics of tramadol users in Denmark, Norway and Sweden.
Methods: Data from the national prescription databases comprising the entire population of Denmark, Norway and Sweden between 2007 and 2015 were used to assess prescription medicine use and sold amount (in defined daily doses (DDDs)) of tramadol, other opioids and non-steroidal anti-inflammatory drugs.
Results: From 2007 to 2015 the prevalence of tramadol users increased in Denmark from 45 to 52 per 1,000 residents, and in Norway from 20 to 41 per 1,000 residents. In Sweden, the prevalence decreased from 36 to 17 per 1,000 residents. In comparison, the prevalence of other opioid users decreased in Denmark and Norway, but increased in Sweden. During the study period, there were more female than male tramadol users in all three countries, and the prevalence of tramadol users tended to increase with age. The average tramadol DDD per treated patient remained fairly constant in Norway, while it increased in Denmark and Sweden. In Denmark and Norway, women received a higher DDD than men. The amount of sold tramadol and other opioids combined per 1,000 residents was highest in Denmark.
Conclusions: From 2007 to 2015, the prescription patterns of tramadol and other opioids differed between the three countries. Tramadol was generally used more frequently by women. Women received higher DDD then men in Norway and Denmark, but not in Sweden. The prevalence of tramadol users tended to increase with age in all countries. |
| format | Article |
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Methods: Data from the national prescription databases comprising the entire population of Denmark, Norway and Sweden between 2007 and 2015 were used to assess prescription medicine use and sold amount (in defined daily doses (DDDs)) of tramadol, other opioids and non-steroidal anti-inflammatory drugs.
Results: From 2007 to 2015 the prevalence of tramadol users increased in Denmark from 45 to 52 per 1,000 residents, and in Norway from 20 to 41 per 1,000 residents. In Sweden, the prevalence decreased from 36 to 17 per 1,000 residents. In comparison, the prevalence of other opioid users decreased in Denmark and Norway, but increased in Sweden. During the study period, there were more female than male tramadol users in all three countries, and the prevalence of tramadol users tended to increase with age. The average tramadol DDD per treated patient remained fairly constant in Norway, while it increased in Denmark and Sweden. In Denmark and Norway, women received a higher DDD than men. The amount of sold tramadol and other opioids combined per 1,000 residents was highest in Denmark.
Conclusions: From 2007 to 2015, the prescription patterns of tramadol and other opioids differed between the three countries. Tramadol was generally used more frequently by women. Women received higher DDD then men in Norway and Denmark, but not in Sweden. The prevalence of tramadol users tended to increase with age in all countries.</description><identifier>ISSN: 2245-1919</identifier><identifier>EISSN: 2245-1919</identifier><identifier>PMID: 32734883</identifier><language>eng</language><publisher>COPENHAGEN: Danish Medical Assoc</publisher><subject><![CDATA[Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Analgesics, Opioid - therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Child ; Child, Preschool ; Databases, Factual ; Denmark - epidemiology ; Drug Prescriptions - statistics & numerical data ; Drug Utilization - statistics & numerical data ; Female ; General & Internal Medicine ; Humans ; Infant ; Infant, Newborn ; Life Sciences & Biomedicine ; Male ; Medicine, General & Internal ; Middle Aged ; Norway - epidemiology ; Practice Patterns, Physicians' - statistics & numerical data ; Prevalence ; Science & Technology ; Sex Factors ; Sweden - epidemiology ; Tramadol - therapeutic use ; Young Adult]]></subject><ispartof>Danish medical journal, 2020-07, Vol.67 (7), Article 06190336</ispartof><rights>Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.</rights><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>5</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000548125000007</woscitedreferencesoriginalsourcerecordid><cites>FETCH-LOGICAL-p211t-f126b4ce0c51ccf411443a508d6f2ae45e65550d18794fd4cc22d3558cd5ff703</cites><orcidid>0000-0002-3777-147X ; 0000-0002-9187-7822</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,28255</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32734883$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schelde, Astrid Blicher</creatorcontrib><creatorcontrib>Sorensen, Anne Mette Skov</creatorcontrib><creatorcontrib>Hindso, Morten</creatorcontrib><creatorcontrib>Christensen, Mikkel Bring</creatorcontrib><creatorcontrib>Jimenez-Solem, Espen</creatorcontrib><creatorcontrib>Eriksson, Robert</creatorcontrib><title>Sex and age differences among tramadol users in three Nordic countries</title><title>Danish medical journal</title><addtitle>DAN MED J</addtitle><addtitle>Dan Med J</addtitle><description>Introduction: The aim of this study was to examine the prevalence and characteristics of tramadol users in Denmark, Norway and Sweden.
Methods: Data from the national prescription databases comprising the entire population of Denmark, Norway and Sweden between 2007 and 2015 were used to assess prescription medicine use and sold amount (in defined daily doses (DDDs)) of tramadol, other opioids and non-steroidal anti-inflammatory drugs.
Results: From 2007 to 2015 the prevalence of tramadol users increased in Denmark from 45 to 52 per 1,000 residents, and in Norway from 20 to 41 per 1,000 residents. In Sweden, the prevalence decreased from 36 to 17 per 1,000 residents. In comparison, the prevalence of other opioid users decreased in Denmark and Norway, but increased in Sweden. During the study period, there were more female than male tramadol users in all three countries, and the prevalence of tramadol users tended to increase with age. The average tramadol DDD per treated patient remained fairly constant in Norway, while it increased in Denmark and Sweden. In Denmark and Norway, women received a higher DDD than men. The amount of sold tramadol and other opioids combined per 1,000 residents was highest in Denmark.
Conclusions: From 2007 to 2015, the prescription patterns of tramadol and other opioids differed between the three countries. Tramadol was generally used more frequently by women. Women received higher DDD then men in Norway and Denmark, but not in Sweden. The prevalence of tramadol users tended to increase with age in all countries.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Databases, Factual</subject><subject>Denmark - epidemiology</subject><subject>Drug Prescriptions - statistics & numerical data</subject><subject>Drug Utilization - statistics & numerical data</subject><subject>Female</subject><subject>General & Internal Medicine</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Life Sciences & Biomedicine</subject><subject>Male</subject><subject>Medicine, General & Internal</subject><subject>Middle Aged</subject><subject>Norway - epidemiology</subject><subject>Practice Patterns, Physicians' - statistics & numerical data</subject><subject>Prevalence</subject><subject>Science & Technology</subject><subject>Sex Factors</subject><subject>Sweden - epidemiology</subject><subject>Tramadol - therapeutic use</subject><subject>Young Adult</subject><issn>2245-1919</issn><issn>2245-1919</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><sourceid>EIF</sourceid><recordid>eNqN0E1LxDAQBuAgirus-xckR0EK-WzToxRXhUUP6rlkk8kaaZs1SVH_vV1WxaNzmTk8DLzvEZozJmRBa1of_7lnaJnSK5mmZKWi5BTNOKu4UIrP0eoRPrAeLNZbwNY7BxEGAwnrPgxbnKPutQ0dHhPEhP2A80sEwPchWm-wCeOQo4d0hk6c7hIsv_cCPa-un5rbYv1wc9dcrYsdozQXjrJyIwwQI6kxTlAqBNeSKFs6pkFIKKWUxFJV1cJZYQxjlkupjJXOVYQv0MXh7y6GtxFSbnufDHSdHiCMqWWC1ZUiNRUTPf-m46YH2-6i73X8bH-yT-DyAN5hE1wyfh_8l011SaEok_viSDVp9X_d-KyzD0Oz74d_ASeYdvk</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Schelde, Astrid Blicher</creator><creator>Sorensen, Anne Mette Skov</creator><creator>Hindso, Morten</creator><creator>Christensen, Mikkel Bring</creator><creator>Jimenez-Solem, Espen</creator><creator>Eriksson, Robert</creator><general>Danish Medical Assoc</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3777-147X</orcidid><orcidid>https://orcid.org/0000-0002-9187-7822</orcidid></search><sort><creationdate>20200701</creationdate><title>Sex and age differences among tramadol users in three Nordic countries</title><author>Schelde, Astrid Blicher ; Sorensen, Anne Mette Skov ; Hindso, Morten ; Christensen, Mikkel Bring ; Jimenez-Solem, Espen ; Eriksson, Robert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-f126b4ce0c51ccf411443a508d6f2ae45e65550d18794fd4cc22d3558cd5ff703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Databases, Factual</topic><topic>Denmark - epidemiology</topic><topic>Drug Prescriptions - statistics & numerical data</topic><topic>Drug Utilization - statistics & numerical data</topic><topic>Female</topic><topic>General & Internal Medicine</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Life Sciences & Biomedicine</topic><topic>Male</topic><topic>Medicine, General & Internal</topic><topic>Middle Aged</topic><topic>Norway - epidemiology</topic><topic>Practice Patterns, Physicians' - statistics & numerical data</topic><topic>Prevalence</topic><topic>Science & Technology</topic><topic>Sex Factors</topic><topic>Sweden - epidemiology</topic><topic>Tramadol - therapeutic use</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Schelde, Astrid Blicher</creatorcontrib><creatorcontrib>Sorensen, Anne Mette Skov</creatorcontrib><creatorcontrib>Hindso, Morten</creatorcontrib><creatorcontrib>Christensen, Mikkel Bring</creatorcontrib><creatorcontrib>Jimenez-Solem, Espen</creatorcontrib><creatorcontrib>Eriksson, Robert</creatorcontrib><collection>Web of Science - Science Citation Index Expanded - 2020</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Danish medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schelde, Astrid Blicher</au><au>Sorensen, Anne Mette Skov</au><au>Hindso, Morten</au><au>Christensen, Mikkel Bring</au><au>Jimenez-Solem, Espen</au><au>Eriksson, Robert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sex and age differences among tramadol users in three Nordic countries</atitle><jtitle>Danish medical journal</jtitle><stitle>DAN MED J</stitle><addtitle>Dan Med J</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>67</volume><issue>7</issue><artnum>06190336</artnum><issn>2245-1919</issn><eissn>2245-1919</eissn><abstract>Introduction: The aim of this study was to examine the prevalence and characteristics of tramadol users in Denmark, Norway and Sweden.
Methods: Data from the national prescription databases comprising the entire population of Denmark, Norway and Sweden between 2007 and 2015 were used to assess prescription medicine use and sold amount (in defined daily doses (DDDs)) of tramadol, other opioids and non-steroidal anti-inflammatory drugs.
Results: From 2007 to 2015 the prevalence of tramadol users increased in Denmark from 45 to 52 per 1,000 residents, and in Norway from 20 to 41 per 1,000 residents. In Sweden, the prevalence decreased from 36 to 17 per 1,000 residents. In comparison, the prevalence of other opioid users decreased in Denmark and Norway, but increased in Sweden. During the study period, there were more female than male tramadol users in all three countries, and the prevalence of tramadol users tended to increase with age. The average tramadol DDD per treated patient remained fairly constant in Norway, while it increased in Denmark and Sweden. In Denmark and Norway, women received a higher DDD than men. The amount of sold tramadol and other opioids combined per 1,000 residents was highest in Denmark.
Conclusions: From 2007 to 2015, the prescription patterns of tramadol and other opioids differed between the three countries. Tramadol was generally used more frequently by women. Women received higher DDD then men in Norway and Denmark, but not in Sweden. The prevalence of tramadol users tended to increase with age in all countries.</abstract><cop>COPENHAGEN</cop><pub>Danish Medical Assoc</pub><pmid>32734883</pmid><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-3777-147X</orcidid><orcidid>https://orcid.org/0000-0002-9187-7822</orcidid></addata></record> |
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| subjects | Adolescent Adult Age Factors Aged Aged, 80 and over Analgesics, Opioid - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Child Child, Preschool Databases, Factual Denmark - epidemiology Drug Prescriptions - statistics & numerical data Drug Utilization - statistics & numerical data Female General & Internal Medicine Humans Infant Infant, Newborn Life Sciences & Biomedicine Male Medicine, General & Internal Middle Aged Norway - epidemiology Practice Patterns, Physicians' - statistics & numerical data Prevalence Science & Technology Sex Factors Sweden - epidemiology Tramadol - therapeutic use Young Adult |
| title | Sex and age differences among tramadol users in three Nordic countries |
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