Astrocytic Ca 2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

Astrocytic Ca signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca signals in the neocortex of awake and naturally sleeping mice while monitoring neuronal Ca activity, brain...

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Veröffentlicht in:	Nature communications 2020-07, Vol.11 (1), p.3240
Hauptverfasser:	Bojarskaite, Laura, Bjørnstad, Daniel M, Pettersen, Klas H, Cunen, Céline, Hermansen, Gudmund Horn, Åbjørsbråten, Knut Sindre, Chambers, Anna R, Sprengel, Rolf, Vervaeke, Koen, Tang, Wannan, Enger, Rune, Nagelhus, Erlend A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism Calcium Signaling Mice Sleep, Slow-Wave - physiology Wakefulness - physiology
Online-Zugang:	Volltext
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