Alternative splicing of ACE2 possibly generates variants that may limit the entry of SARS-CoV-2: a potential therapeutic approach using SSOs

Angiotensin-converting enzyme 2 (ACE2) plays an essential role in maintaining the balance of the renin-angiotensin system and also serves as a receptor for the SARS-CoV-2, SARS-CoV, and HCoV-NL63. Following the recent outbreak of SARS-CoV-2 infection, there has been an urgent need to develop therape...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical science (1979) 2020-05, Vol.134 (10), p.1143-1150
Hauptverfasser:	Rehman, Sayeed Ur, Tabish, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Angiotensin-Converting Enzyme 2 Betacoronavirus - physiology Computational Biology Coronavirus Infections - genetics Coronavirus Infections - therapy COVID-19 Exons Humans Life Sciences & Biomedicine Medicine, Research & Experimental Models, Molecular Oligonucleotides, Antisense - pharmacology Pandemics Peptidyl-Dipeptidase A - genetics Pneumonia, Viral - genetics Pneumonia, Viral - therapy Protein Domains Receptors, Virus - genetics Research & Experimental Medicine SARS-CoV-2 Science & Technology Virus Internalization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!