Decreased expression of GBA3 correlates with a poor prognosis in hepatocellular carcinoma patients

Beta-glucosidase (GBA), also known as acid β-glucosidase, exhibits an activity of glucosylceramidase (EC 3.2.1.45). Three main isoforms of β-glucosidases have been identified in mammals: GBA1, GBA2, and GBA3. The deficiency of these enzymes leads to glucosylceramide accumulation, resulting in Gauche...

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Veröffentlicht in:	Neoplasma 2020-01, Vol.67 (5), p.1139-1145
Hauptverfasser:	Ying, J F, Zhang, Y N, Song, S S, Hu, Z M, He, X L, Pan, H Y, Zhang, C W, Wang, H J, Li, W F, Mou, X Z
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Glucosidase - genetics Biomarkers, Tumor Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - genetics Humans Immunohistochemistry Liver Neoplasms - diagnosis Liver Neoplasms - genetics Prognosis
Online-Zugang:	Volltext
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