Clinical Applications of Chromosomal Microarray Testing in Myeloid Malignancies

Purpose of Review Knowledge of both somatic mutations and copy number aberrations are important for the understanding of cancer pathogenesis and management of myeloid neoplasms. The currently available standard of care technologies for copy number assessment such as conventional karyotype and FISH a...

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Veröffentlicht in:	Current hematologic malignancy reports 2020-06, Vol.15 (3), p.194-202
Hauptverfasser:	Ronaghy, Arash, Yang, Richard K., Khoury, Joseph D., Kanagal-Shamanna, Rashmi
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Aberrations Chromosomes, Human Comparative Genomic Hybridization DNA Copy Number Variations Genetic Predisposition to Disease Geriatrics/Gerontology Hematology High-Throughput Nucleotide Sequencing Humans Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - genetics Leukemia, Myelomonocytic, Chronic - diagnosis Leukemia, Myelomonocytic, Chronic - genetics Life Sciences & Biomedicine Loss of Heterozygosity Medicine Medicine & Public Health Microarray Analysis Molecular Testing and Diagnostics (J Khoury Myelodysplastic Syndromes - diagnosis Myelodysplastic Syndromes - genetics Oncology Polymorphism, Single Nucleotide Predictive Value of Tests Prognosis Reproducibility of Results Science & Technology Section Editor Topical Collection on Molecular Testing and Diagnostics
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