Longitudinal Monitoring of ctDNA in Patients with Melanoma and Brain Metastases Treated with Immune Checkpoint Inhibitors

Purpose: Brain involvement occurs in the majority of patients with metastatic melanoma. The potential of circulating tumor DNA (ctDNA) for surveillance and monitoring systemic therapy response in patients with melanoma brain metastases merits investigation. Experimental Design: This study examined c...

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Veröffentlicht in:Clinical cancer research 2020-08, Vol.26 (15), p.4064-4071
Hauptverfasser: Lee, Jenny H., Menzies, Alexander M., Carlino, Matteo S., McEvoy, Ashleigh C., Sandhu, Shahneen, Weppler, Alison M., Diefenbach, Russell J., Dawson, Sarah-Jane, Kefford, Richard F., Millward, Michael J., Al-Ogaili, Zeyad, Tra, Thien, Gray, Elin S., Wong, Stephen Q., Scolyer, Richard A., Long, Georgina, Rizos, Helen
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Sprache:eng
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