TSLP drives acute T H 2-cell differentiation in lungs

Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine that is important for the development of type 2 inflammatory responses at mucosal surfaces. In humans, TSLP level has been found to be elevated in the lungs of patients with asthma, and in mouse models, TSLP can promote type 2 air...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2020-12, Vol.146 (6), p.1406
Hauptverfasser:	Lai, Jen-Feng, Thompson, Lucas J, Ziegler, Steven F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma - immunology Asthma - pathology Cell Differentiation - immunology Cytokines - immunology Disease Models, Animal Lung - immunology Lung - pathology Macrophages - immunology Macrophages - pathology Mice Mice, Inbred BALB C Monocytes - immunology Monocytes - pathology Pulmonary Eosinophilia - immunology Pulmonary Eosinophilia - pathology Th2 Cells - immunology Th2 Cells - pathology
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