Pathophysiology of AKI to CKD progression

Acute kidney injury (AKI), defined as a rapid decrease in glomerular filtration rate, is a common and devastating pathologic condition. AKI is associated with significant morbidity and subsequent chronic kidney disease (CKD) development. Regardless of the initial insult, CKD progression after AKI in...

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Veröffentlicht in:	Seminars in nephrology 2020-03, Vol.40 (2), p.206-215
Hauptverfasser:	Sato, Yuki, Takahashi, Masahiro, Yanagita, Motoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute kidney injury Acute Kidney Injury - immunology Acute Kidney Injury - metabolism Acute Kidney Injury - physiopathology Age Factors Aged Animals chronic inflammation Disease Progression Disease Susceptibility fibroblast Fibroblasts - immunology Fibroblasts - metabolism Fibrosis Glomerular Filtration Rate Humans Inflammation - immunology Inflammation - metabolism Inflammation - physiopathology Ischemia - metabolism Ischemia - physiopathology Kidney - pathology Kidney - physiology Kidney Tubules, Proximal - immunology Kidney Tubules, Proximal - metabolism Kidney Tubules, Proximal - physiopathology Mitochondria - metabolism Monocytes - immunology Neutrophils - immunology proximal tubule Regeneration Renal Insufficiency, Chronic - immunology Renal Insufficiency, Chronic - metabolism Renal Insufficiency, Chronic - physiopathology T-Lymphocytes - immunology Tertiary Lymphoid Structures - immunology tertiary lymphoid tissues
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