Irradiated tumor cell-derived microparticles mediate tumor eradication via cell killing and immune reprogramming

Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical indications remains challenging. The mechanism underlying the radiation-induced bystander effect (RIBE) is not understood and not therapeutically exploited. We suggest that the RIBE is predominantly mediated by ir...

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Veröffentlicht in:	Science advances 2020-03, Vol.6 (13), p.eaay9789-eaay9789, Article 9789
Hauptverfasser:	Wan, Chao, Sun, Yajie, Tian, Yu, Lu, Lisen, Dai, Xiaomeng, Meng, Jingshu, Huang, Jing, He, Qianyuan, Wu, Bian, Zhang, Zhanjie, Jiang, Ke, Hu, Desheng, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Multidisciplinary Sciences SciAdv r-articles Science & Technology Science & Technology - Other Topics
Online-Zugang:	Volltext
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