Quercetin-loaded nanoparticles enhance cytotoxicity and antioxidant activity on C6 glioma cells

Quercetin (Qu) is a natural flavonoid present in many commonly consumed food items. The dietary phytochemical quercetin prevents tumor proliferation and is a potent therapeutic cancer agent. The purpose of this study was to synthesize and characterize quercetin-loaded poly(lactic-co-glycolic acid) n...

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Veröffentlicht in:	Pharmaceutical development and technology 2020-07, Vol.25 (6), p.757-766
Hauptverfasser:	Ersoz, Melike, Erdemir, Aysegul, Derman, Serap, Arasoglu, Tulin, Mansuroglu, Banu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antioxidant activity Antioxidants - pharmacokinetics Antioxidants - toxicity C6 glioma Cell Line, Tumor Cell Survival - drug effects Cell Survival - physiology cytotoxicity Cytotoxins - pharmacokinetics Cytotoxins - toxicity Glioma - drug therapy Glioma - metabolism nanoparticle Nanoparticles - metabolism Nanoparticles - toxicity Particle Size PLGA Quercetin Quercetin - pharmacokinetics Quercetin - toxicity Rats
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