BRAINSTORM: A Multi-Institutional Phase 1/2 Study of RRx-001 in Combination With Whole Brain Radiation Therapy for Patients With Brain Metastases

To determine the recommended phase 2 dose of RRx-001, a radiosensitizer with vascular normalizing properties, when used with whole-brain radiation therapy (WBRT) for brain metastases and to assess whether quantitative changes in perfusion magnetic resonance imaging (MRI) after RRx-001 correlate with...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2020-07, Vol.107 (3), p.478-486
Hauptverfasser:	Kim, Michelle M., Parmar, Hemant A., Schipper, Matthew, Devasia, Theresa, Aryal, Madhava P., Kesari, Santosh, O’Day, Steven, Morikawa, Aki, Spratt, Daniel E., Junck, Larry, Mammoser, Aaron, Hayman, James A., Lawrence, Theodore S., Tsien, Christina I., Aiken, Robert, Goyal, Sharad, Abrouk, Nacer, Trimble, Malcolm, Cao, Yue, Lao, Christopher D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Azetidines - therapeutic use Brain Neoplasms - diagnostic imaging Brain Neoplasms - secondary Brain Neoplasms - therapy Carcinoma, Non-Small-Cell Lung - pathology Chemoradiotherapy Cranial Irradiation Female Humans Lung Neoplasms - pathology Magnetic Resonance Imaging Male Middle Aged Nitro Compounds - therapeutic use Radiation-Sensitizing Agents - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!