Photo-oxidation of lysozyme triggered by riboflavin is O 2 -dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter-molecular crosslinks

Photosensitized protein oxidation is a promising tool for medical procedures such as photochemical tissue bonding (PTB). We have recently reported that the binding of rose Bengal, a sensitizer employed in PTB, to lysozyme modulates the photooxidation and crosslinking of this protein. In this work we...

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Veröffentlicht in:Free radical biology & medicine 2020-05, Vol.152, p.61
Hauptverfasser: Fuentes-Lemus, Eduardo, Mariotti, Michele, Reyes, Juan, Leinisch, Fabian, Hägglund, Per, Silva, Eduardo, Davies, Michael J, López-Alarcón, Camilo
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Sprache:eng
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