Multi-stimuli responsive nanogel/hydrogel nanocomposites based on κ-carrageenan for prolonged release of levodopa as model drug

This study describes the development of a novel biocompatible nanogel/hydrogel nanocomposite system for long-term delivery of bioactive molecules. To this aim, the nanogels were synthesized via radical polymerization of poly(N-isopropylacrylamide). The nanogels were introduced during the formation o...

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Veröffentlicht in:	International journal of biological macromolecules 2020-06, Vol.153, p.180-189
Hauptverfasser:	Bardajee, Ghasem Rezanejade, Khamooshi, Nastaran, Nasri, Shima, Vancaeyzeele, Cédric
Format:	Artikel
Sprache:	eng
Schlagworte:	Carrageenan - chemistry Controlled drug release Delayed-Action Preparations - chemistry Delayed-Action Preparations - pharmacokinetics Drug Carriers - chemistry Drug Carriers - pharmacokinetics Levodopa Levodopa - chemistry Levodopa - pharmacokinetics Magnetic iron oxide nanoparticles Nanogel/hydrogel composite Nanogels - chemistry Soft nanocomposites
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