The Magnitude of the Warfarin‐Amiodarone Drug‐Drug Interaction Varies With Renal Function: A Propensity‐Matched Cohort Study

Amiodarone inhibits warfarin metabolism and is associated with major bleeding during warfarin therapy. Managing this drug‐drug interaction (DDI) is challenging because of substantial interpatient variability in DDI magnitude. Because renal dysfunction induces changes in drug metabolism and protein b...

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