Joint study of the associations of HLA-B and the transmembrane STR polymorphism of MICA with alopecia areata shows independent associations of both of them with the disease

Alopecia areata is a skin disease that produces hair loss in patches of skin. The underlying mechanism of alopecia areata is a loss of immune privilege by hair follicles, which are then attacked by NK cells. A genome-wide association study (GWAS) linked single nucleotide polymorphisms (SNPs) of MHC...

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Veröffentlicht in:Clinical and experimental dermatology 2020-02
Hauptverfasser: Mingorance Gámez, C G, Martínez Chamorro, A, Moreno Casares, A M, Tercedor Sánchez, J, Arias-Santiago, S, García-Lora, A, López-Nevot, M A
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Sprache:eng
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