New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration

Skeletal muscle fibrosis and impaired muscle regeneration are major contributors to muscle wasting in Duchenne muscular dystrophy (DMD). Muscle growth is negatively regulated by myostatin (MSTN) and activins. Blockage of these pathways may improve muscle quality and function in DMD. Antisense oligon...

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Veröffentlicht in:	The FASEB journal 2017-01, Vol.31 (1), p.238
Hauptverfasser:	Pasteuning-Vuhman, Svitlana, Boertje-van der Meulen, Johanna W, Putten, Maaike Van, Overzier, Maurice, Ten Dijke, Peter, Kielbasa, Szymon M, Arindrarto, Wibowo, Wolterbeek, Ron, Lezhnina, Ksenia V, Ozerov, Ivan V, Aliper, Aleksandr M, Hoogaars, Willem M, Aartsma-Rus, Annemieke, Loomans, Cindy J M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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