Detection of ALK Gene Rearrangement in Cell-free RNA from Lung Cancer Malignant Pleural Effusion

The aim of this study was to evaluate the feasibility of measuring ALK gene rearrangement in cell-free RNA (cf-RNA) of the supernatant from malignant pleural effusion (MPE). Supernatant, cell blocks, and matched sera samples were collected. Cf-RNA was isolated from the supernatant and sera, and cell...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-5, Article 6124106
Hauptverfasser:	Luo, Meng, Zhang, Zhuxue, Hu, Jianjun, Zhu, Yanqiu, Chu, Mingliang, Ma, Xiaobo
Format:	Artikel
Sprache:	eng
Schlagworte:	Age ALK protein Biotechnology & Applied Microbiology Cancer Crizotinib Deoxyribonucleic acid DNA Gene rearrangement Genes Genetic aspects Life Sciences & Biomedicine Lung cancer Medicine, Research & Experimental Mutation Patients Pleural effusion Pleural effusions Polymerase chain reaction Research & Experimental Medicine Ribonucleic acid RNA Science & Technology Studies
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