Hypoxia-Induced Oxygen Tolerance: Maintenance of Endothelial Metabolic Function

Hypoxia (10%-12% O2) preadaptation for 4-7 days effectively protects rats from oxygen toxicity. The present study was designed to investigate the hypothesis that the lung's microvascular endothelium shares in development of oxygen tolerance and therefore that endothelial metabolic function woul...

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Veröffentlicht in:	Exp. Lung Res.; (United States) 1988, Vol.14 (S1), p.887-896
Hauptverfasser:	Jackson, Robert M., Ann, Hyung Soo, Oparil, Suzanne
Format:	Artikel
Sprache:	eng
Schlagworte:	550501 - Metabolism- Tracer Techniques Adaptation, Physiological ANIMAL TISSUES ANIMALS ANOXIA BASIC BIOLOGICAL SCIENCES BETA DECAY RADIOISOTOPES BIOLOGICAL ADAPTATION BIOLOGICAL EFFECTS BIOLOGICAL FUNCTIONS BIOLOGICAL MARKERS BODY DAYS LIVING RADIOISOTOPES Dipeptides - metabolism Drug Tolerance ELECTRON CAPTURE RADIOISOTOPES ELEMENTS ENDOTHELIUM Endothelium, Vascular - metabolism ENZYME ACTIVITY ENZYME INHIBITORS ENZYMES FUNCTIONS HYDROLASES Hypoxia - metabolism Hypoxia - physiopathology IN VITRO In Vitro Techniques INTERMEDIATE MASS NUCLEI IODINE 125 IODINE ISOTOPES Iodine Radioisotopes ISOTOPE APPLICATIONS ISOTOPES Male MAMMALS METABOLISM NONMETALS NUCLEI ODD-EVEN NUCLEI ORGANS OXYGEN Oxygen - pharmacology PEPTIDE HYDROLASES PERFUSED ORGANS RADIOISOTOPES RATS Rats, Inbred Strains RODENTS TISSUES TRACER TECHNIQUES VERTEBRATES
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