Enzyme-free amplified SERS immunoassay for the ultrasensitive detection of disease biomarkers

We developed a novel enzyme-free amplified SERS immunoassay by combining silver nanoparticle (AgNP)-linked immunoreaction and SERS transduction for the detection of disease biomarkers. As a proof of concept, our method was successfully illustrated with the disease biomarker α-fetoprotein with the de...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (19), p.2933-2936
Hauptverfasser:	Zhang, Xuan-Xuan, Xu, Duo, Guo, Dan, Han, Huan-Xing, Li, Da-Wei, Ma, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Biomarkers Biomarkers - blood Disease control Double-Blind Method Enzymes Humans Immunoassay Immunoassay - methods Limit of Detection Metal Nanoparticles - chemistry Nanoparticles Proof of Concept Study Reproducibility of Results Silver Silver - chemistry Spectrum Analysis, Raman - methods
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