Acetylene Group, Friend or Foe in Medicinal Chemistry

The use of an acetylene (ethynyl) group in medicinal chemistry coincides with the launch of the Journal of Medicinal Chemistry in 1959. Since then, the acetylene group has been broadly exploited in drug discovery and development. As a result, it has become recognized as a privileged structural featu...

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Veröffentlicht in:	Journal of medicinal chemistry 2020-06, Vol.63 (11), p.5625-5663
1. Verfasser:	Talele, Tanaji T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
Online-Zugang:	Volltext
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