Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma

Neoantigens present unique and specific targets for personalized cancer immunotherapy strategies. Given the low mutational burden yet immunotherapy responsiveness of malignant mesothelioma (MM) when compared to other carcinogen-induced malignancies, identifying candidate neoantigens and T cells that...

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Veröffentlicht in:	Oncoimmunology 2020-01, Vol.9 (1), p.1684713
Hauptverfasser:	Sneddon, Sophie, Rive, Craig M., Ma, Shaokang, Dick, Ian M., Allcock, Richard J. N., Brown, Scott D., Holt, Robert A., Watson, Mark, Leary, Shay, Lee, Y. C. Gary, Robinson, Bruce W. S., Creaney, Jenette
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - genetics CD8-Positive T-Lymphocytes - immunology Humans Immunotherapy Malignant mesothelioma Mesothelioma, Malignant - immunology neoantigen Original Research pleural effusion Receptors, Cell Surface tumor-immune interface
Online-Zugang:	Volltext
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