High-throughput analysis of cell-cell crosstalk in ad hoc designed microfluidic chips for oncoimmunology applications

Understanding the interactions between immune and cancer cells occurring within the tumor microenvironment is a prerequisite for successful and personalized anti-cancer therapies. Microfluidic devices, coupled to advanced microscopy systems and automated analytical tools, can represent an innovative...

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Veröffentlicht in:	Methods in enzymology 2020, Vol.632, p.479
Hauptverfasser:	Mencattini, Arianna, De Ninno, Adele, Mancini, Jacopo, Businaro, Luca, Martinelli, Eugenio, Schiavoni, Giovanna, Mattei, Fabrizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Immunological - pharmacology Cell Communication - drug effects Cell Line, Tumor Drug Screening Assays, Antitumor - instrumentation Drug Screening Assays, Antitumor - methods Equipment Design Female Humans Lab-On-A-Chip Devices Mice Mice, Inbred C57BL Microfluidic Analytical Techniques - instrumentation Microfluidic Analytical Techniques - methods Neoplasms - drug therapy Neoplasms - immunology Tumor Microenvironment - drug effects
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