Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis
We sought to determine the main factors related to relapse in patients with substance-related disorders (SRDs) who received methadone maintenance therapy (MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers in Kermansh...
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creator | Matin , Behzad Karami Moradinazar , Mehdi Rezaeian , Shahab Farnia , Vahid Rezaei , Satar Alikhani , Mostafa Karyani , Ali Kazemi Najafi , Farid |
description | We sought to determine the main factors related to relapse in patients with
substance-related disorders (SRDs) who received methadone maintenance therapy
(MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional
study of 4175 patients referred to the 45 MMT centers in Kermanshah province,
west of Iran. We included all patients who were under MMT for at least one year. All
information was collected through an interview by a psychologist. Descriptive statistics
and univariate and multiple regression models were used in statistical analysis. The Gini
index was calculated to determine the cut-off point of nodes. We used the Classification
and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6%
for all participants, with no significant gender differences. The DT resulted in a five-level
model of significant factors affecting substance abuse relapse. These included lower cost
for buying substances, lower age at first substance use, history of quitting substances
without medication, frequency of substances utilization per month, and frequency of
methadone therapy. Conclusions: Knowing the main factors associated with substance
abuse relapse could be important for health care providers to make better decisions for
improving the treatment outcomes of SRDs. |
doi_str_mv | 10.5001/omj.2020.07 |
format | Article |
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substance-related disorders (SRDs) who received methadone maintenance therapy
(MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional
study of 4175 patients referred to the 45 MMT centers in Kermanshah province,
west of Iran. We included all patients who were under MMT for at least one year. All
information was collected through an interview by a psychologist. Descriptive statistics
and univariate and multiple regression models were used in statistical analysis. The Gini
index was calculated to determine the cut-off point of nodes. We used the Classification
and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6%
for all participants, with no significant gender differences. The DT resulted in a five-level
model of significant factors affecting substance abuse relapse. These included lower cost
for buying substances, lower age at first substance use, history of quitting substances
without medication, frequency of substances utilization per month, and frequency of
methadone therapy. Conclusions: Knowing the main factors associated with substance
abuse relapse could be important for health care providers to make better decisions for
improving the treatment outcomes of SRDs.</description><identifier>ISSN: 1999-768X</identifier><identifier>ISSN: 2070-5204</identifier><identifier>EISSN: 2070-5204</identifier><identifier>DOI: 10.5001/omj.2020.07</identifier><identifier>PMID: 31993227</identifier><language>eng</language><publisher>Muscat - Oman: Oman Medical Specialty Board</publisher><subject>decision trees ; DISORDERS ; IRAN ; METHADONE ; Original ; PATIENTS ; substance-related disorders ; THERAPY ; إيران ; الإضطرابات ; العلاج ; المتادون ; المرضى</subject><ispartof>Oman medical journal, 2020-01, Vol.35 (1), p.1-7</ispartof><rights>The OMJ is Published Bimonthly and Copyrighted 2020 by the OMSB.</rights><rights>The OMJ is Published Bimonthly and Copyrighted 2020 by the OMSB. 2020 Oman Medical Specialty Board</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a4077-42b4052ba8223e01cbd9ec7f2451941ad0c0ccca76d24112196ccd9a33ade5163</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttps://static.almanhal.com/covers/titl/146373/cover-lg.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976887/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976887/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31993227$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Matin , Behzad Karami</creatorcontrib><creatorcontrib>Moradinazar , Mehdi</creatorcontrib><creatorcontrib>Rezaeian , Shahab</creatorcontrib><creatorcontrib>Farnia , Vahid</creatorcontrib><creatorcontrib>Rezaei , Satar</creatorcontrib><creatorcontrib>Alikhani , Mostafa</creatorcontrib><creatorcontrib>Karyani , Ali Kazemi</creatorcontrib><creatorcontrib>Najafi , Farid</creatorcontrib><title>Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis</title><title>Oman medical journal</title><addtitle>Oman Med J</addtitle><description>We sought to determine the main factors related to relapse in patients with
substance-related disorders (SRDs) who received methadone maintenance therapy
(MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional
study of 4175 patients referred to the 45 MMT centers in Kermanshah province,
west of Iran. We included all patients who were under MMT for at least one year. All
information was collected through an interview by a psychologist. Descriptive statistics
and univariate and multiple regression models were used in statistical analysis. The Gini
index was calculated to determine the cut-off point of nodes. We used the Classification
and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6%
for all participants, with no significant gender differences. The DT resulted in a five-level
model of significant factors affecting substance abuse relapse. These included lower cost
for buying substances, lower age at first substance use, history of quitting substances
without medication, frequency of substances utilization per month, and frequency of
methadone therapy. Conclusions: Knowing the main factors associated with substance
abuse relapse could be important for health care providers to make better decisions for
improving the treatment outcomes of SRDs.</description><subject>decision trees</subject><subject>DISORDERS</subject><subject>IRAN</subject><subject>METHADONE</subject><subject>Original</subject><subject>PATIENTS</subject><subject>substance-related disorders</subject><subject>THERAPY</subject><subject>إيران</subject><subject>الإضطرابات</subject><subject>العلاج</subject><subject>المتادون</subject><subject>المرضى</subject><issn>1999-768X</issn><issn>2070-5204</issn><issn>2070-5204</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkU1vEzEQhi0EolHpiTNo72hTf-06viChQmmlVq2gSNysWXu267BZR7bTqv8ep6Gh9WU8M8-8tuYl5D2j84ZSdhxWyzmnnM6pekVmnCpaN5zK12TGtNa1ahe_D8hRSktajtBcC_6WHIjSFJyrGflzCjaHmKofOEJGV-XweF0nrPxUXUP2OOVU3fs8VD83XcowWayf6K8-heiwzG-mEqpLzAO4MGF1CX7KOG3p6mbACOuHd-RND2PCo3_xkPw6_XZzclZfXH0_P_lyUYOkStWSd5I2vIMF5wIps53TaFXPZcO0ZOCopdZaUK3jkjHOdGut0yAEOGxYKw7J-U7XBViadfQriA8mgDePhRBvDcTs7YhGitZqSwG1tNJyB9D20GFJddNK2xetzzut9aZbobNlGRHGF6IvO5MfzG24M60uu1-oIvBpJ2BjSCliv59l1GwtNMVCs7XQ0C398flze_bJsAJ82AFY6tjDntBNw9TivwCMK5iGZ19lshVKiL8Mg64E</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Matin , Behzad Karami</creator><creator>Moradinazar , Mehdi</creator><creator>Rezaeian , Shahab</creator><creator>Farnia , Vahid</creator><creator>Rezaei , Satar</creator><creator>Alikhani , Mostafa</creator><creator>Karyani , Ali Kazemi</creator><creator>Najafi , Farid</creator><general>Oman Medical Specialty Board</general><general>OMJ</general><scope>~6Z</scope><scope>ADJCN</scope><scope>AHFXO</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20200101</creationdate><title>Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy</title><author>Matin , Behzad Karami ; Moradinazar , Mehdi ; Rezaeian , Shahab ; Farnia , Vahid ; Rezaei , Satar ; Alikhani , Mostafa ; Karyani , Ali Kazemi ; Najafi , Farid</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a4077-42b4052ba8223e01cbd9ec7f2451941ad0c0ccca76d24112196ccd9a33ade5163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>decision trees</topic><topic>DISORDERS</topic><topic>IRAN</topic><topic>METHADONE</topic><topic>Original</topic><topic>PATIENTS</topic><topic>substance-related disorders</topic><topic>THERAPY</topic><topic>إيران</topic><topic>الإضطرابات</topic><topic>العلاج</topic><topic>المتادون</topic><topic>المرضى</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matin , Behzad Karami</creatorcontrib><creatorcontrib>Moradinazar , Mehdi</creatorcontrib><creatorcontrib>Rezaeian , Shahab</creatorcontrib><creatorcontrib>Farnia , Vahid</creatorcontrib><creatorcontrib>Rezaei , Satar</creatorcontrib><creatorcontrib>Alikhani , Mostafa</creatorcontrib><creatorcontrib>Karyani , Ali Kazemi</creatorcontrib><creatorcontrib>Najafi , Farid</creatorcontrib><collection>Al Manhal All Journals Collection</collection><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Oman medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matin , Behzad Karami</au><au>Moradinazar , Mehdi</au><au>Rezaeian , Shahab</au><au>Farnia , Vahid</au><au>Rezaei , Satar</au><au>Alikhani , Mostafa</au><au>Karyani , Ali Kazemi</au><au>Najafi , Farid</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis</atitle><jtitle>Oman medical journal</jtitle><addtitle>Oman Med J</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>35</volume><issue>1</issue><spage>1</spage><epage>7</epage><pages>1-7</pages><issn>1999-768X</issn><issn>2070-5204</issn><eissn>2070-5204</eissn><abstract>We sought to determine the main factors related to relapse in patients with
substance-related disorders (SRDs) who received methadone maintenance therapy
(MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional
study of 4175 patients referred to the 45 MMT centers in Kermanshah province,
west of Iran. We included all patients who were under MMT for at least one year. All
information was collected through an interview by a psychologist. Descriptive statistics
and univariate and multiple regression models were used in statistical analysis. The Gini
index was calculated to determine the cut-off point of nodes. We used the Classification
and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6%
for all participants, with no significant gender differences. The DT resulted in a five-level
model of significant factors affecting substance abuse relapse. These included lower cost
for buying substances, lower age at first substance use, history of quitting substances
without medication, frequency of substances utilization per month, and frequency of
methadone therapy. Conclusions: Knowing the main factors associated with substance
abuse relapse could be important for health care providers to make better decisions for
improving the treatment outcomes of SRDs.</abstract><cop>Muscat - Oman</cop><pub>Oman Medical Specialty Board</pub><pmid>31993227</pmid><doi>10.5001/omj.2020.07</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | decision trees DISORDERS IRAN METHADONE Original PATIENTS substance-related disorders THERAPY إيران الإضطرابات العلاج المتادون المرضى |
title | Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis |
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