Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis

We sought to determine the main factors related to relapse in patients with substance-related disorders (SRDs) who received methadone maintenance therapy (MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers in Kermansh...

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Veröffentlicht in:Oman medical journal 2020-01, Vol.35 (1), p.1-7
Hauptverfasser: Matin , Behzad Karami, Moradinazar , Mehdi, Rezaeian , Shahab, Farnia , Vahid, Rezaei , Satar, Alikhani , Mostafa, Karyani , Ali Kazemi, Najafi , Farid
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container_issue 1
container_start_page 1
container_title Oman medical journal
container_volume 35
creator Matin , Behzad Karami
Moradinazar , Mehdi
Rezaeian , Shahab
Farnia , Vahid
Rezaei , Satar
Alikhani , Mostafa
Karyani , Ali Kazemi
Najafi , Farid
description We sought to determine the main factors related to relapse in patients with substance-related disorders (SRDs) who received methadone maintenance therapy (MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers in Kermanshah province, west of Iran. We included all patients who were under MMT for at least one year. All information was collected through an interview by a psychologist. Descriptive statistics and univariate and multiple regression models were used in statistical analysis. The Gini index was calculated to determine the cut-off point of nodes. We used the Classification and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6% for all participants, with no significant gender differences. The DT resulted in a five-level model of significant factors affecting substance abuse relapse. These included lower cost for buying substances, lower age at first substance use, history of quitting substances without medication, frequency of substances utilization per month, and frequency of methadone therapy. Conclusions: Knowing the main factors associated with substance abuse relapse could be important for health care providers to make better decisions for improving the treatment outcomes of SRDs.
doi_str_mv 10.5001/omj.2020.07
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Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers in Kermanshah province, west of Iran. We included all patients who were under MMT for at least one year. All information was collected through an interview by a psychologist. Descriptive statistics and univariate and multiple regression models were used in statistical analysis. The Gini index was calculated to determine the cut-off point of nodes. We used the Classification and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6% for all participants, with no significant gender differences. The DT resulted in a five-level model of significant factors affecting substance abuse relapse. These included lower cost for buying substances, lower age at first substance use, history of quitting substances without medication, frequency of substances utilization per month, and frequency of methadone therapy. 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subjects decision trees
DISORDERS
IRAN
METHADONE
Original
PATIENTS
substance-related disorders
THERAPY
إيران
الإضطرابات
العلاج
المتادون
المرضى
title Factors Related to Relapse in Patients with Substance-Related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis
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