Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime

The release of inflammatory bacterial products, such as lipopolysaccharide (LPS)/endotoxin, may be increased upon the administration of antibiotics. An improved quantitative understanding of endotoxin release and its relation to antibiotic exposure and bacterial growth/killing may be gained by an in...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2020-03, Vol.64 (4)
Hauptverfasser:	Thorsted, Anders, Tano, Eva, Kaivonen, Kia, Sjölin, Jan, Friberg, Lena E, Nielsen, Elisabet I
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Cefuroxime - pharmacology Escherichia coli - drug effects Farmaceutisk vetenskap Lipopolysaccharides - metabolism Microbial Sensitivity Tests Models, Theoretical Pharmaceutical Science Pharmacology
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