Tryptophan metabolite-regulated Treg responses contribute to attenuation of airway inflammation during specific immunotherapy in a mouse asthma model

In allergen-specific immunotherapy for asthma, antigens attached to dendritic cells increase the tryptophan metabolism in these cells and alter the Th17/Treg balance in the airways. Tryptophan metabolism has long been suggested to be relevant in the pathophysiology of allergic disorders, including a...

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Veröffentlicht in:	Human vaccines & immunotherapeutics 2020-08, Vol.16 (8), p.1891-1899
Hauptverfasser:	Hu, Qi, Jin, Ling, Zeng, Jing, Wang, Jinyu, Zhong, Shimin, Fan, Wenting, Liao, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	3 dioxygenase Allergen immunotherapy asthma IgE indoleamine 2 regulatory T cells Research Paper tryptophan metabolite
Online-Zugang:	Volltext
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