VIP and muscarinic synergistic mucin secretion by salivary mucous cells is mediated by enhanced PKC activity via VIP-induced release of an intracellular Ca 2+ pool

Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via increased intracellular free calcium ([Ca ] ) and activation of conventional protein kinase C isozymes (cPKC). However, the parasympathetic co-neuro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pflügers Archiv 2020-03, Vol.472 (3), p.385
Hauptverfasser:	Culp, David J, Zhang, Z, Evans, R L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Animals Bodily Secretions - metabolism Calcium - metabolism Cholinergic Agents - pharmacology Isoenzymes - metabolism Male Mucins - metabolism Muscarinic Agonists - pharmacology Phorbol Esters - pharmacology Protein Kinase C - metabolism Rats Rats, Wistar Receptors, Muscarinic - metabolism Salivary Glands - drug effects Salivary Glands - metabolism Thapsigargin - pharmacology Vasoactive Intestinal Peptide - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!