Eomes transcription factor is required for the development and differentiation of invariant NKT cells

Eomes regulates the differentiation of CD8 T cells into effector and memory phases. However, its role in invariant (i)NKT cells remains unknown. Here, we show the impact of Eomes on iNKT cells in the thymus and peripheral tissue using conditional knockout (Eomes-cKO) mice. In the thymus, CD1d-tetram...

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Veröffentlicht in:	Communications biology 2019-04, Vol.2 (1), p.150
Hauptverfasser:	Shimizu, Kanako, Sato, Yusuke, Kawamura, Masami, Nakazato, Hiroshi, Watanabe, Takashi, Ohara, Osamu, Fujii, Shin-Ichiro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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