Beclin 1 regulates recycling endosome and is required for skin development in mice

Beclin 1 is a key regulator of autophagy and endocytosis. However, its autophagy-independent functions remain poorly understood. Here, we report that Beclin 1 regulates recycling endosome and is required for skin development in vivo. We first established keratinocyte-specific Beclin 1-knockout mice...

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Veröffentlicht in:Communications biology 2019-01, Vol.2 (1), p.37
Hauptverfasser: Noguchi, Saori, Honda, Shinya, Saitoh, Tatsuya, Matsumura, Hiroyuki, Nishimura, Emi, Akira, Shizuo, Shimizu, Shigeomi
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Sprache:eng
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