Efficient synthesis and cell migration inhibitory effect of substituted benzamidothiazolylpyrazole-capped AWDI-NH 2

Substituted (2-benzamidothiazol-5-yl)pyrazole-capped AWD*I-NH were synthesized and their antimigration activity was studied. The improved efficiency and scalability of the analog synthesis was achieved via a late-stage diversification of the benzoyl group and a convergent route in which the bisazole...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2020-02, Vol.30 (4), p.126914
Hauptverfasser: Yang, Mian, Chen, Jun, Peng, Wancai, Li, Qiqi, Shao, Hui, Tang, Guanping, Zhang, Tong-Cun, Takada, Yoshikazhu, Ye, Long, Liao, Xing-Hua
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Sprache:eng
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