Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3

Resveratrol (RES) has a protective effect on osteoarthritis (OA), nevertheless, the underlying mechanisms of RES towards obesity-related OA are still unclear. This study is aimed to determine whether leptin resistant mechanism presents in articular cartilage of obesity-related OA and whether the pro...

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Veröffentlicht in:Toxicology and applied pharmacology 2020-02, Vol.388, p.114871, Article 114871
Hauptverfasser: Jiang, Mengqi, He, Jianyi, Gu, Hailun, Yang, Yingchun, Huang, Yue, Xu, Xiaolei, Liu, Li
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Sprache:eng
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