Biocatalytic Amplification of UV Signal in Capillary Electrophoresis of MicroRNA

MicroRNAs (miRNAs) are new potential biomarkers for early diagnosis and classification of cancer. This study is the first attempt to use biocatalytic amplification reactions combined with capillary electrophoresis to detect multiple miRNAs simultaneously. In this way, miRNAs, as catalysts, can catal...

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Veröffentlicht in:	International journal of molecular sciences 2019-12, Vol.21 (1), p.51, Article 51
Hauptverfasser:	Hu, Ruibin, Chen, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocatalysis Biochemistry & Molecular Biology Biomarkers Biomarkers, Tumor - genetics Capillary electrophoresis Catalysis Catalysts Chemistry Chemistry, Multidisciplinary Deoxyribonucleic acid Design DNA Early Detection of Cancer Electrophoresis Electrophoresis, Capillary - methods Feasibility Studies Humans Hybridization Life Sciences & Biomedicine Limit of Detection MicroRNAs MicroRNAs - genetics miRNA Neoplasms - diagnosis Neoplasms - genetics Nucleic Acid Amplification Techniques - methods Nucleic acids Physical Sciences Quantitative analysis Science & Technology Selectivity Tumors Ultraviolet Rays
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