Development and optimization of levodopa and benzylhydrazine orally disintegrating tablets by direct compression and response surface methodology

The number of Parkinson's disease (PD) patients with the advanced phase and motor fluctuations is increasing. The objective of this study is developing levodopa/benzylhydrazine orally disintegrating tablets (L/B ODTs), which would provide greater convenience and ease of use than conventional ta...

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Veröffentlicht in:	Drug development and industrial pharmacy 2020-01, Vol.46 (1), p.42-49
Hauptverfasser:	Zhang, Yuanyuan, Li, Zewen, Tang, Hui, Ren, Wenjie, Gao, Xin, Sun, Yangjian, Zhao, Qiu Xiang, Wang, Fanye, Liu, Junhong
Format:	Artikel
Sprache:	eng
Schlagworte:	benzylhydrazine direct compression Levodopa orally disintegrating tablets (ODTs) response surface methodology
Online-Zugang:	Volltext
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