Nutritional Management of Nonalcoholic fatty liver disease (NAFLD)

Nonalcoholic fatty liver disease (NAFLD) is strongly associated with obesity and insulin resistance. There is currently no pharmacological treatment validated in steatosis. The combination of weight loss and adequate physical activity can improve liver steatosis. In randomized trials and cohort stud...

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Veröffentlicht in:La Presse médicale (1983) 2019-12, Vol.48 (12), p.1496
Hauptverfasser: Ait Boudaoud, Amel, Rives-Lange, Claire, Perregaux, Jean François, Radu, Alina, Messager-Josipowicz, Diane, Barsamian, Charles, Carette, Claire, Czernichow, Sébastien
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Sprache:eng ; fre
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Zusammenfassung:Nonalcoholic fatty liver disease (NAFLD) is strongly associated with obesity and insulin resistance. There is currently no pharmacological treatment validated in steatosis. The combination of weight loss and adequate physical activity can improve liver steatosis. In randomized trials and cohort studies, a weight loss of at least 7% and a diet approaching the Mediterranean diet have been associated with an improvement in hepatic fat content, an improvement in hepatic biomarkers, and regression of histological signs of steatosis. Bariatric surgery by losing weight can lead to an improvement in hepatic fat content.
ISSN:2213-0276
DOI:10.1016/j.lpm.2019.10.026