Prostaglandin D 2 stimulates phenotypic changes in vascular smooth muscle cells

Since chronic inflammation is associated with the pathogenesis of atherosclerosis, inflammatory cytokines might contribute to the phenotypic modulation of vascular smooth muscle cells (VSMCs). Tumor necrosis factor α (TNFα) facilitated the transformation of contractile VSMCs to the synthetic phenoty...

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Veröffentlicht in:	Experimental & molecular medicine 2019-11, Vol.51 (11), p.1
Hauptverfasser:	Lee, Hye Sun, Yun, Sung Ji, Ha, Jung Min, Jin, Seo Yeon, Ha, Hong Koo, Song, Sang Heon, Kim, Chi Dae, Bae, Sun Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cells, Cultured Cyclooxygenase 2 - metabolism Immunohistochemistry Lentivirus - genetics Male Mice Mice, Mutant Strains Muscle, Smooth, Vascular - cytology Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - drug effects Phenotype PPAR gamma - metabolism Prostaglandin D2 - pharmacology Rats Rats, Sprague-Dawley Signal Transduction - drug effects Tumor Necrosis Factor-alpha - metabolism
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