Loss of Ca 2+ entry via Orai-TRPC1 induces ER stress, initiating immune activation in macrophages

Activation of cellular stresses is associated with inflammation; however, the mechanisms are not well identified. Here, we provide evidence that loss of Ca influx induces endoplasmic reticulum (ER) stress in primary macrophages and in murine macrophage cell line Raw 264.7, in which the unfolded prot...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of cell science 2019-12, Vol.133 (5)
Hauptverfasser:	Nascimento Da Conceicao, Viviane, Sun, Yuyang, Zboril, Emily K, De la Chapa, Jorge J, Singh, Brij B
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!