A novel electrochemical sensor based on microporous polymeric nanospheres for measuring peroxynitrite anion released by living cells and studying the synergistic effect of antioxidants

Peroxynitrite anion (ONOO − ) is a crucial reactive nitrogen species (RNS), which has aroused immense research interest in the biological and biomedical fields because aberrant expression levels of ONOO − are related to many diseases. In this work, a novel electrochemical sensor is described for the...

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Veröffentlicht in:	Analyst (London) 2019-11, Vol.144 (23), p.695-6913
Hauptverfasser:	Liu, Fuxin, Li, Lin, Zhang, Binyan, Fan, Weizhou, Zhang, Rongjin, Liu, Guoan, Liu, Xiuhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Anions Antioxidants Antioxidants - pharmacology Carbon - chemistry Cell Line, Tumor Cells (biology) Chemical sensors Chitosan Chitosan - chemistry Drug Synergism Electrochemical Techniques - methods Electrodes Glassy carbon Humans Limit of Detection Metals, Heavy - pharmacology Nanocomposites Nanospheres Nanospheres - chemistry Nitrogen Oxidative Stress - drug effects Peroxynitrous Acid - analysis Peroxynitrous Acid - metabolism Porosity Reproducibility of Results Scavenging Sensors Synergistic effect
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