Enhanced liposome-mediated antibacterial activity of piperacillin and gentamicin against gram-negative bacilli in vitro

Abstract This study showed that encapsulation of piperacillin (PIP) and gentamicin (GE) by liposomes prepared with phosphatidylcholine and cholesterol (1:1) enhanced the antibiotic activity against gram negative bacilli. This was demonstrated by growth inhibition of Escherichia coli and Pseudomonas...

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Veröffentlicht in:	Journal of microencapsulation 1988, Vol.5 (4), p.303-309
Hauptverfasser:	Nacucchio, Marcelo C., Gatto Bellora, Mauricio J., Sordelli, Daniel O., D'aquino, Miguel
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Carriers Drug Resistance, Microbial Escherichia coli Escherichia coli - drug effects Gentamicins - pharmacology Liposomes Penicillin Resistance Piperacillin - pharmacology Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects
Online-Zugang:	Volltext
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