Pumpless microfluidic devices for generating healthy and diseased endothelia

We have developed a pumpless cell culture chip that can recirculate small amounts of cell culture medium (400 μL) in a unidirectional flow pattern. When operated with the accompanying custom rotating platform, the device produces an average wall shear stress of up to 0.588 Pa ± 0.006 Pa without the...

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Veröffentlicht in:	Lab on a chip 2019-09, Vol.19 (19), p.3212-3219
Hauptverfasser:	Yang, Yang, Fathi, Parinaz, Holland, Glenn, Pan, Dipanjan, Wang, Nam Sun, Esch, Mandy B
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Cell culture Cytokines Endothelial cells Endothelium Human Umbilical Vein Endothelial Cells - cytology Humans Interleukins Linings Microfluidic Analytical Techniques - instrumentation Microfluidic devices Wall shear stresses
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