A biotinylated ruthenium() photosensitizer for tumor-targeted two-photon photodynamic therapy

Platinum-resistant cancer cells are sensitive to changes in the levels of reactive oxidative species (ROS). Herein, we design a biotin-modified Ru( ii ) complex as a photosensitizer (denoted as Ru-Biotin). Ru-Biotin can selectively target cancer cells and produce vast amounts of singlet oxygen under...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019-09, Vol.55 (73), p.1972-1975
Hauptverfasser:	Li, Jia, Zeng, Leli, Xiong, Kai, Rees, Thomas W, Jin, Chengzhi, Wu, Weijun, Chen, Yu, Ji, Liangnian, Chao, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biotin Cancer Design modifications Photodynamic therapy Photons Platinum Ruthenium compounds Singlet oxygen
Online-Zugang:	Volltext
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