MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME WITH CHLORPHENIRAMINE MALEATE, MANNITOL, AND INVASIVE HEMODYNAMIC MONITORING
Ovarian hyperstimulation syndrome due to exogenous gonadotropin administration is life-threatening in its most severe form. Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (p...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1988-03, Vol.71 (3, Part 2 Suppl), p.485-487 |
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| container_end_page | 487 |
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| container_issue | 3, Part 2 Suppl |
| container_start_page | 485 |
| container_title | Obstetrics and gynecology (New York. 1953) |
| container_volume | 71 |
| creator | Kirshan, Brian Doody, Michael C Cotton, David B Gibbons, William |
| description | Ovarian hyperstimulation syndrome due to exogenous gonadotropin administration is life-threatening in its most severe form. Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (previously shown to be effective in animal models) and invasive hemodynamic monitoring. Mannitol and albumin infusions were also used to maintain urine output and intravascular volume. |
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Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (previously shown to be effective in animal models) and invasive hemodynamic monitoring. Mannitol and albumin infusions were also used to maintain urine output and intravascular volume.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 3126472</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Adult ; Biological and medical sciences ; Chlorpheniramine - therapeutic use ; Female ; Fertilization in Vitro ; Genital system. Reproduction ; Gonadotropins - adverse effects ; Hemodynamics ; Humans ; Mannitol - therapeutic use ; Medical sciences ; Monitoring, Physiologic ; Ovarian Diseases - chemically induced ; Ovarian Diseases - drug therapy ; Ovulation Induction ; Pharmacology. 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Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (previously shown to be effective in animal models) and invasive hemodynamic monitoring. Mannitol and albumin infusions were also used to maintain urine output and intravascular volume.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Chlorpheniramine - therapeutic use</subject><subject>Female</subject><subject>Fertilization in Vitro</subject><subject>Genital system. Reproduction</subject><subject>Gonadotropins - adverse effects</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Mannitol - therapeutic use</subject><subject>Medical sciences</subject><subject>Monitoring, Physiologic</subject><subject>Ovarian Diseases - chemically induced</subject><subject>Ovarian Diseases - drug therapy</subject><subject>Ovulation Induction</subject><subject>Pharmacology. Drug treatments</subject><subject>Syndrome</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kF1PwjAYhRejQUR_gkkvvHRJv9aulw0U1mRryZgoV6SMLqBDyQYhJv54ZyBevSfveXIunqugj2JOQkzI23XQhxCLkMeU3gZ3bfsOIURMkF7QIwgzynE_-MmkkROVKVMAOwZ2LnMtDUgWU5XPCp29pLLQ1oDZwoxymynwqosEDJPU5tNEGZ3LTBsFMpkqWajnLhijC5s-A2lGQJu5nOm5AonK7GhhOngIMvtH5NpM7oObytWtf7jcQVCMVTFMwtRO9FCm4R7HEIWCE7GOYMwhZhWkGJURc1WEfQUj5GjFozUTLGasWnsa85X3tCw5XDlROkY9GQSP59n9cbXz6-W-2e5c8728SOj6p0vv2tLVVeM-y237jzEheMRRh9EzdvqqD75pP-rjyTfLjXf1YbPs3EKGIxgiEceQdKbD7oMR-QUbtWvU</recordid><startdate>198803</startdate><enddate>198803</enddate><creator>Kirshan, Brian</creator><creator>Doody, Michael C</creator><creator>Cotton, David B</creator><creator>Gibbons, William</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>198803</creationdate><title>MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME WITH CHLORPHENIRAMINE MALEATE, MANNITOL, AND INVASIVE HEMODYNAMIC MONITORING</title><author>Kirshan, Brian ; Doody, Michael C ; Cotton, David B ; Gibbons, William</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2801-9739d5087026f0421c56af52ef051a4f75d696866fde487bee4cc70ba9ca64e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Chlorpheniramine - therapeutic use</topic><topic>Female</topic><topic>Fertilization in Vitro</topic><topic>Genital system. Reproduction</topic><topic>Gonadotropins - adverse effects</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Mannitol - therapeutic use</topic><topic>Medical sciences</topic><topic>Monitoring, Physiologic</topic><topic>Ovarian Diseases - chemically induced</topic><topic>Ovarian Diseases - drug therapy</topic><topic>Ovulation Induction</topic><topic>Pharmacology. Drug treatments</topic><topic>Syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kirshan, Brian</creatorcontrib><creatorcontrib>Doody, Michael C</creatorcontrib><creatorcontrib>Cotton, David B</creatorcontrib><creatorcontrib>Gibbons, William</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kirshan, Brian</au><au>Doody, Michael C</au><au>Cotton, David B</au><au>Gibbons, William</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME WITH CHLORPHENIRAMINE MALEATE, MANNITOL, AND INVASIVE HEMODYNAMIC MONITORING</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1988-03</date><risdate>1988</risdate><volume>71</volume><issue>3, Part 2 Suppl</issue><spage>485</spage><epage>487</epage><pages>485-487</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Ovarian hyperstimulation syndrome due to exogenous gonadotropin administration is life-threatening in its most severe form. Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (previously shown to be effective in animal models) and invasive hemodynamic monitoring. Mannitol and albumin infusions were also used to maintain urine output and intravascular volume.</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>3126472</pmid><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1988-03, Vol.71 (3, Part 2 Suppl), p.485-487 |
| issn | 0029-7844 1873-233X |
| language | eng |
| recordid | cdi_pubmed_primary_3126472 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Biological and medical sciences Chlorpheniramine - therapeutic use Female Fertilization in Vitro Genital system. Reproduction Gonadotropins - adverse effects Hemodynamics Humans Mannitol - therapeutic use Medical sciences Monitoring, Physiologic Ovarian Diseases - chemically induced Ovarian Diseases - drug therapy Ovulation Induction Pharmacology. Drug treatments Syndrome |
| title | MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME WITH CHLORPHENIRAMINE MALEATE, MANNITOL, AND INVASIVE HEMODYNAMIC MONITORING |
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